If you’re working in fertility care, you already know how tricky endometrium assessment can be: unstandardized measurements, time-consuming image reviews, and readings. That’s exactly why we built ENDOSCAN: an AI for endometrium assessment tool, designed to take the uncertainty out of endometrium ultrasound analysis, so you can focus on what matters most: your patients.

ENDOSCAN is an AI-powered ultrasound tool that helps fertility professionals perform faster and more standardized endometrium assessment. It automates critical steps such as measuring endometrium thickness and volume, recognizing morphological patterns like the triple-line and detecting intrauterine fluid. By streamlining these processes with AI for IVF, ENDOSCAN reduces variability, saves time and provides reliable, data-based insights. This means greater efficiency for clinical teams, more confidence in decision-making and ultimately better outcomes for patients undergoing fertility treatment.

What is ENDOSCAN?

ENDOSCAN is an AI-based tool that automatically analyzes 2D and 3D ultrasound scans of the endometrium. It measures key parameters like:

• Endometrium thickness (ET)
• Endometrium volume, in mm³

Thanks to seamless integration with ultrasound machines, it fits right into your clinic’s routine with no extra steps, no additional equipment, and no friction. 

 

Thickness still counts

There’s no doubt that endometrial thickness plays a big role in IVF outcomes:

A large retrospective clinical study on medicated frozen embryo transfers (FETs) found that cycles with endometrial thickness (EMT) of 6–7 mm had substantially lower outcomes:

Clinical pregnancy rate: 44.1%

Live birth rate: 32.1%

In contrast, patients with EMT ≥ 9 mm fared much better.

 

A  different study also analyzed outcomes across both fresh and frozen-thawed embryo transfer cycles. It found that:

Clinical pregnancy and live birth rates remained optimal at EMT between 11–12 mm (so-called sweet-spot).

The lowest rates occurred when EMT was < 6 mm

Miscarriage rates were lowest at EMT of 11–12 mm

Volume is more than a bonus

Endometrial volume often flies under the radar, but research is catching up. Several studies link increased endometrial volume and vascularization with higher pregnancy chances, especially around the trigger day and embryo transfer.

 

 

Why ENDOSCAN could help you 

Confidence in every scan

Instead of manual and varying interpretations, ENDOSCAN offers standardized measurements, preventing errors and variability between clinicians.

You can also rely on automation for your follicular exams. That’s why we built FOLLISCAN: an AI-powered tool for automatic detection and measurement of follicles of all sizes.  Check out FOLLISCAN.

Fast, seamless, no disruptions

You don’t need to change how you work. ENDOSCAN fits naturally into your scanning routine, works with your existing US systems and delivers its analysis in real time with zero additional effort from your team.

Tested across borders

The tool has been developed with the input of clinics across Europe and the U.S., so it’s built to work with diverse patient populations and ultrasound platforms. It’s flexible, reliable and ready to scale.

Smarter IVF starts here

ENDOSCAN is a smarter way to assess endometrial health in IVF. It brings consistency to your evaluations, saves valuable time and delivers clinically relevant insights that support better outcomes for both your team and your patients.

Want to see ENDOSCAN in action?

ENDOSCAN is currently undergoing certification but we are already working with IVF clinics as a Research Use Tool.  If you would like to try ENDOSCAN or participate in a validation study, please request a demo.

 

 

BIBLIOGRAPHY

1.Kasius, A., Smit, J. G., Torrance, H.L., Eijkemans, M., Mol B. W.,  Opmeer, B., Broekmans, F., (2014) Endometrial thickness and pregnancy rates after IVF: a systematic review and meta-analysis, Human Reproduction Update, Volume 20, Issue 4, Pages 530–541, https://doi.org/10.1093/humupd/dmu011

2. Jayaram, S., Rashmi, K., (2022) Endometrial thickness as a predictor of pregnancy outcomes in assisted reproductive techniques: A prospective observational study from southern India., Int J Clin Obstet Gynaecol., 6(1):195‑198, doi:10.33545/gynae.2021.v5.i6c.1645    

3. Değer, U., Kalı, Z., Çağıran F., (2023). Endometrial thickness is a good predictor of clinical pregnancy and live birth rates in fresh and frozen-thawed embryo transfer cycles. European Review for Medical and Pharmacological Sciences, 27(13), 6351–6358. https://doi.org/10.26355/eurrev_202307_3299

4. Aboulghar, M. A.,  Aboulghar, M. M., (2023). Optimum endometrial thickness before embryo transfer: An ongoing debate. Fertility and Sterility, 120(1), 99–100

5.  Mathyk, B., Schwartz, A., DeCherney, A., (2023) A critical appraisal of studies on endometrial thickness and embryo transfer outcome. Reprod BioMed Volume 47, Issue 4, Available from: https://www.rbmojournal.com/article/S1472-6483%2823%2900359-0/fulltext, access: 09.09.2025

6. Gao, G., Cui, X., Li, S., Ding, P., Zhang, S., Zhang, Y., (2020), Endometrial thickness and IVF cycle outcomes: a meta-analysis, Reproductive BioMedicine Online, Volume 40, Issue 1, Pages 124-133, ISSN 1472-6483, https://doi.org/10.1016/j.rbmo.2019.09.005 

7.  Huang W, Tang J, Wei L, Nong L, Tang N, Wei X, (2025), Association of endometrial thickness with live birth rates among women undergoing fresh IVF, FET and PGT cycles. Front Cell Dev Biol. 13:1530953. doi:10.3389/fcell.2025.1530953 

8. Eftekhar, M., Mehrjardi, S.Z., Molaei, B. , (2020), The correlation between endometrial thickness and pregnancy outcomes in fresh ART cycles with different age groups: a retrospective study. Middle East Fertil Soc J 24, 10, https://doi.org/10.1186/s43043-019-0013-y